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Islets from white B6 mice were transplanted into eyes from 10-week-old female NOD.Rag2 -/- recipient mice (n=4) and non-inflamed islets from NOD.Rag2 -/- mice were transplanted into eyes from 7-week-old female white B6.Rag -/- mice (n=3)

Other studies have demonstrated successful rescue of neurological and electrophysiological deficits in adult Ube3a Stop/p+ mice after reactivation of the Ube3a gene and rescue of neurological defects in adult Mecp2 lox-Stop/y mice after reactivation of the Mecp2 gene [183,184,185]

So the key is: Will you benefit