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Like all peptides, it's vulnerable to enzymatic degradation when exposed to the gastrointestinal (GI) tract

Fortunately, studies have actually shown changing to a his tamine-free die t for only 4 weeks can show improvements of histamine intolerance symptoms as well as serum histamine levels

J Exp Bot 60:12071218 Doke N (1985) NADPH-dependent superoxide generation in membrane fractions isolated from wounded potato tubers inoculated with Phytopthora infestans

243:575586 Birben E, Sahiner UM, Sackesen C, Erzurum S, Kalayci O (2012) Oxidative stress and antioxidant defense

This broader approach helps support batch consistency, transparency, and overall product quality