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Glutathione exists in two primary forms: the reduced form (GSH), characterized by a free sulfhydryl group (-SH) on its cysteine residue, and the oxidized form, glutathione disulfide (GSSG), which is formed when two GSH molecules are linked via a disulfide bond between their cysteine residues during redox reactions

By examining Mn homeostasis mechanisms, including Mn absorption, excretion, distribution, and transport across the intestines, liver, and brain, this work highlights the integrative nature of Mn physiology