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The BENDIP study demonstrated that neuropathic symptoms, measured using the NIS as the primary endpoint, improved after 6 weeks of treatment with benfotiamine at a dose of 300 mg twice daily (no improvement was observed with 300 mg once daily) [71]

Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 18(10), 22262233.e4

Angiogenesis in chronic liver disease and its complications

The post says rigorous trials examining concurrent use are limited and safety data from large randomized trials remain sparse for this specific pairing, which is why clinicians who do prescribe both typically reserve it for refractory cases with intensive monitoring

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