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In a partial hepatectomy-induced behavior study using male Sprague-Dawley rats, surgical trauma induced an exacerbated spatial learning and memory impairment, while exendin-4 treatment suppressed the activation of nuclear factor kappa-B (NF-B) and IL-1, and thus ameliorated hepatectomy-induced behavioral deficits and inflmmation (63)

With its demonstrated effectiveness, the medication has become a popular option, but the high cost remains a barrier for many

These uses of GLP-1RA beyond the proven use in treatment and prevention of cardiovascular risk with obesity (110) as well as in diabetics add a new dimension to use them in early

However, its essential to discuss these options with your healthcare provider to determine the best course of action based on your personal health needs and goals

Final thought: 91% maintained their weight through week 48 without regain