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Zou J, Song Q, Shaw PC, Wu Y, Zuo Z, Yu R

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Moses MA, Wiederschain D, Loughlin KR, Zurakowski D, Lamb CC, Freeman MR

After intestinal absorption, in enterocytes, LCFAs get activated (i.e., fused with CoA to form an acyl-CoAa form in which fatty acids can enter various metabolic pathways) and esterified, trigger chylomicron formation and get transported via lymph, whereas MCFAs largely avoid activation and are primarily transported directly to the liver through the portal vein