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Combined inhibition of nitric oxide and vasodilating prostaglandins abolishes forearm vasodilatation to systemic hypoxia in healthy humans

Increases of GTP (2.4-fold in plasma), uridine, and xanthine (2.8- and 4.0-fold in blood, respectively) were also prominent (Table 1)

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Gastrointestinal effects: Nausea and vomiting, which are among the most commonly reported side effects of retatrutide, can themselves contribute to dizziness through fluid loss and general malaise