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These metabolic actions within the nervous system leading to the generation of ATP that is necessary for a) the synthesis of mitochondrial DNA neurons, b) for the formation of melanin axonal sheath, c) to provide the biochemical components of neurotransmission d) to maintain the constancy of the internal environment neuronal necessary to generate action potentials and allow transmission at synapses (Neurology, 1995, 45: 11-16)

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