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This makes it difficult to compare between individuals or draw objective conclusions from human data

Using a landmark analysis at 6 weeks, the authors confirmed that irAEs of any grade were an independent predictor of higher overall response rate (ORR), longer OS and more prolonged PFS [45]

Over the last several decades, the pharmaceutical industry pursued melanocortin-4 receptor-selective agonists for the treatment of general obesity

and (3) reported performance metrics of safety and/or efficacy (e.g., assessment of effectiveness in tumor response, pain response, tumor volume reduction, adverse events (AEs))

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