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Description

While endogenous IGF-1 is produced in the liver in response to growth hormone (GH), LR3 is engineered for enhanced performance with a half-life of 2030 hours compared to IGF-1s natural 2030 minutes

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A Study of Retatrutide (LY3437943) in Adults With Obesity and Knee Osteoarthritis (TRIUMPH-4)

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In the SURMOUNT-1 trial, tirzepatide participants lost up to 20.9% of body weight over 72 weeks, outperforming semaglutide in head-to-head comparisons

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doi:10.1172/JCI28773

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A., DiPasquale, G

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