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This frequency balances maintaining therapeutic levels in the joint while allowing time for tissue regeneration processes to occur

The standard regimen is 1mg injections three times weekly for two weeks, followed by maintenance doses of 1mg every 2-3 months

Importantly, these body weight changes were not attributable to differences in food intake across the groups, as all treatments showed similar food consumption patterns in both lean and obese mice

The authors also noted the critical limitation: no human data exists to confirm whether these effects translate to clinical outcomes in people

Studies on obese rodents showed that AOD9604 impacted weight loss through many mechanisms