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By this point I was down to 172 pounds and feeling better than I had in a decade

Menopause causes estrogen decline, which slows metabolism by up to 5% and increases hunger signals in the brain

That has limited sustained use, especially because these medicines are typically taken over months and often longer

A total of 32 channel-combined, water-suppressed spectra were acquired using a semi-LASER 1 H-MRS pulse sequence (TR = 7500 ms, TE = 100 ms) during each scan session, while participants were at rest and asked to stare at a white cross on a black screen for 4 min

PMID: 29249689 | doi:10.1016/j.cmet.2017.11.002 Tang QQ et al