2007 Oral melanoacanthoma and oral melanotic macule: a report of 8 cases, review of the literature, and immunohistochemical analysis Romn Carlos-Bregni 1 , Elisa Contreras 1 , Ana Carolina Netto 1 , Adalberto Mosqueda-Taylor 2 , Pablo Agustin Vargas 3 , Jacks Jorge 3 , Jorge Esquiche Len 3 , Oslei Paes de Almeida 3 (1) Departamento de Patologa y Medicina Oral, Centro Clnico de Cabeza y Cuello, Guatemala (2) Departamento de Atencin a la Salud, Universidad Autnoma Metropolitana Xochimilco
Silymarin is thought to be responsible for most of the plant's beneficial effects
1 2 "Chemical and Physical Properties"
The same body of research also found that higher doses of GHK-Cu can produce skin irritation, and that copper in general is highly toxic, which is why formulation and concentration matter considerably in any experimental design involving this compound
One of the primary effects is increased vulnerability to hemolytic anemia, where red blood cells break down prematurely due to oxidative damage
