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The steps including the release of product and the incorporation of new substrate are indicated by the outlined arrows.

Identification of the FATP2-KOregulated factors that stimulate islet hypertrophy will require further investigation

In addition to LC3, several groups have developed some specific macrophage substrates to monitor autophagic flux, such as p62/SQSTM1 (151, 152), BRCA1 gene 1 protein (NBR1) (151), betaine-homocysteine s-methyltransferase (153), and polyglutamine protein aggregates (154)

Unlike traditional antidiabetic drugs, GLP-1 analogs leverage the peptide's ability to stimulate insulin release while minimizing hypoglycemia risk

2010 Dec;11(12):1803-18