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Although the treatment policy estimand (which uses data regardless of treatment discontinuation and rescue medication use) was the primary estimand in PIONEER 2 and PIONEER 3, it was inappropriate to use it for a long-term cost-effectiveness analysis without adjusting for the clinical effects and associated costs of rescue medication used during the study

Overall, antidrug antibodies were deemed not to have a significant impact on safety

Kaufman and the anti-desmin antibody (D3) developed by Dr

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Whether or not meloxicam transfers to babies through breast milk is unclear