When insulin is ineffective, more glucose winds up floating around in your blood, which prompts your pancreas to overcompensate and produce even more insulin, Dr
This same mechanism powers medications like semaglutide (Ozempic/Wegovy), but Retatrutide goes further
That comparison is from the studied FDA-approved products under trial conditions - it's relevant context for understanding why tirzepatide's higher efficacy average might justify its slightly higher price point, but it doesn't predict the gap in any individual patient's results
(Top holdings, as of January 16, 2025, below): Source: Amplify ETFs The Roundhill GLP-1 & Weight Loss ETF (OZEM) is another ETF in this segment, also launched in May 2024
Plus, more muscle means higher metabolic rate and better glucose disposal (insulin sensitivity), both of which support fat loss