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This means you don't need to layer medications to see substantial, durable outcomes

doi: 10.1136/bmjdrc-2023-003666 11 VallabhajosyulaSMasterVGurellMN

Viral Shah, an endocrinologist at Indiana University School of Medicine, told CNN in 2025 that people 65 and older are already at risk for sarcopenia, and losing even 10 to 15% of lean mass while on a GLP-1 is significant because they have less muscle to begin with

There are numerous studies in the general population and among patients with chronic kidney disease that show glucagon-like peptide-1 (GLP-1) medications are safe and effective for weight loss. Formed in March 2024, the Comprehensive Transplant Centers kidney transplant weight loss program uses a combination of diet, exercise, counseling and weight loss injection medication to help patients reach weight loss goals to make them eligible for transplantation