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Metformin primarily reduces liver glucose output and improves peripheral insulin sensitivity through AMPK activation

It belongs to a class of drugs known as glucagon-like peptide-1 (GLP-1) receptor agonists , which work by mimicking the action of a naturally occurring hormone in the body that regulates blood sugar levels

Our study differs fundamentally from the reported research on SETDB1 51 in both mechanistic focus and molecular targets

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Visfatin through STAT3 activation enhances IL-6 expression that promotes endothelial angiogenesis