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Since cannabis is a Schedule 1 medication in the U.S., marijuana use is prohibited in some states but permitted for both medical and recreational use in others

Although the prevalence of mental illness has increased over recent years, the reasons for the increased prevalence of mental disorders remain unclear

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In a 2-year carcinogenicity study in Sprague Dawley rats, subcutaneous doses of 0.0025, 0.01, 0.025 and 0.1 mg/kg/day were administered (below quantification, 0.2-, 0.4-, and 2-fold the exposure at the MRHD)

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