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They found that the indole-based molecules have superiority over previously tested inhibitors

Detection of Inhibition of 5-Aminoimidazole-4-Carboxamide Ribotide Transformylase by Thioinosinic Acid and Azathioprine by a New Colorimetric Assay

This means that taking a Vitamin C supplement is going to be of little help if our cells have insufficient glutathione

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While for the Clathrin box, the predicted peptide position matches our experimental data, discrepancies are obtained for the Arrestin box, where AF2 failed to correctly place the Sla1 peptide (depicted within dashed red circles in Supplementary Fig 6)