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Tirzepatide GLP-1/GIP Active ingredient in Mounjaro and Zepbound

Good brands include RXBAR, Quest, ONE Bars, Built Bar, and Kirkland Signature from Costco

The drug candidate acts as an agonist of the glucagon-like peptide-1 (GLP-1) receptor, following the same mode of action as Mounjaro (tirzepatide), the companys peptide-based GLP-1 drug for weight loss

It enhances the activity of CREB, a transcription factor that regulates the expression of genes involved in memory consolidation, and promotes the production of BDNF, or brain-derived neurotrophic factor, a protein that acts as a kind of molecular fertilizer for neurons, supporting their survival, growth, and the formation of new synaptic connections [15]

Still, Saxenda remains available and may have a role for specific patients