Kardie Tobb, DO, MS, FASPC, FACC, a boardcertified preventive cardiologist and the medical director for the Cone Health HeartCare Women's Heart Health and Cardio-Obstetrics Clinic, explains some of the most common reasons why GLP-1s may not deliver the results you're hoping for, including: You need a higher dose and have not yet reached a therapeutic dose as determined by your doctor High intake of liquid calories , including alcohol and ultra-processed foods Not getting enough protein , which can leave you persistently hungry and makes it harder to feel full Advanced diabetes or insulin resistance Taking other medications such as sulfonylureas, which lower blood sugar but can lead to weight gain Not adhering to your dosing schedule , such as inconsistent weekly injections or missed doses Differences in gut hormones or genetics And just because your GLP-1 isn't working immediately doesn't mean it won't work for you
Speak to your pharmacist or GP before making any changes to your treatment
GLP-1 receptor agonists include semaglutide, dulaglutide, and liraglutide, used for type 2 diabetes and weight management
Learn how you can start your journey with Bonnie Lea Davis, FNP-C your dedicated GLP-1 weight loss provider
Why four-week intervals matter Four weeks is not arbitrary
