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Se supplementation in euthyroid, subclinical, or overt hypothyroid patients not only reduced thyroid autoantibodies, lowered or maintained TSH, decreased fT4/fT3 ratio, but also decreased OS and inflammation, and improved quality of life, structure, and volume thyroid gland (79)

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Results GSH depletion induces cell death in RPE cells To evaluate the effect of GSH depletion on the RPE cells, we used three different approaches: depletion of Cys 2 from cell culture media, treatment with buthionine sulphoximine (BSO, 1000 M) to block de novo synthesis of GSH, or treatment with erastin (10 M), an inhibitor of system x c 1

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