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Instead, it leverages the UKPDS82 dataset [29], which inherently incorporates the combined effects of these risk factors as observed longitudinally in a well-characterized cohort, within this analytical framework, HbA1c reductions observed in the SUSTAIN 7 trial [22] function as a primary, though not exclusive, determinant of microvascular risk, and as one of several contributors to macrovascular risk, against the background of the integrated risk profile emulated by the UKPDS structure

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Continued treatment with tirzepatide for maintenance of weight reduction in adults with obesity

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