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Cystine appeared to be the main regulator of GSH homeostasis (among other amino acids), since cystine deprivation alone reduced intracellular GSH and it was not further aggravated by depletion of other amino acids

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These findings underscore the conserved nature of metabolic dysregulation across different PH subtypes and models, highlighting glycolytic reprogramming as a fundamental feature of PH pathophysiology

Trends in spontaneous and indicated preterm delivery among singleton gestations in the United States, 2005-2012

& Marraffini, L