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Third, the assumption of comparability across trials may not fully account for differences in adherence, treatment intensification strategies, or background care, which could affect the magnitude of treatment effects

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It adds to the growing body of evidence suggesting that GLP-1 receptor agonists may have neuroprotective properties, which could benefit patients beyond glucose control. However, as a clinician, Im also aware of the need for further research, including longer-term studies and randomized controlled trials, to better understand the mechanisms and validate these findings before making changes to my treatment approach, she added

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