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They can address multiple eczema mechanisms simultaneously, unlike most conventional drugs that target single pathways

The change in bone age, for those with measurements after at least 1 year of treatment up to a maximum 17 years of treatment, exceeded the change in chronological age by a mean of 0.9 years (SD = 1.8) (+ 7.4 years [SD = 3.7] versus + 6.5 years [SD = 3.7], respectively)

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Based on these observations, it is most likely that the age-related change in GH secretion is multifactorial in etiology and is primarily caused by changes above the pituitary level

Cudaback, E., Yang, Y., Montine, T