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Rather than dissolving immediately upon contact with gastric fluid, the capsule protects its contents until reaching the small intestine

While cagrilintide did not significantly alter fat or lean mass in RAMP 1/3 KO mice compared to vehicle-treated KO mice (Fig

Furthermore, overexpressing SLC25A40 in SLC25A39 knockout cells was sufficient to restore mitochondrial GSH levels, suggesting its redundant function in enabling mitochondrial GSH import alongside SLC25A39 (Fig

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