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Not based on current data

5ad) and had no acute or chronic effect on mitochondrial functions in differentiated BAT primary cells, including mitochondrial respiration, proton production rate, proton leak respiration, coupling efficiency, maximal substrate oxidation, cellular respiration, non-mitochondrial and mitochondrial respiration, ATP-linked respiration, glycolysis, glycolytic proton production rate and glycolytic and oxidative phosphorylation-linked ATP production (Extended Data Fig

Whilst glucagon typically raises blood glucose, early Phase 2 trial data suggest that, when combined with GLP-1 receptor activation, its net effect may include increased calorie burning and a potential reduction in liver fat, without causing clinically significant rises in blood sugar

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