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The anti-androgen effect persists because spironolactone's active metabolite, canrenone, has a half-life of 13 to 24 hours, making once-daily morning dosing pharmacologically sufficient for hormonal indications

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Although the addition of L-carnitine did not result in statistically significant differences in perceived color, higher concentrations appeared to reduce consumer appeal in terms of visual perception

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Future studies will reveal the applicability of our model, for example, to activate enzymatically inactive glutaredoxins, to alter the sensitivity and responsiveness of glutaredoxin-coupled fluorescent redox sensors, to further address the catalytic mechanism with GSSCys, HEDS and physiological substrates, or to design specific transition-state inhibitors