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Studies suggest muscle loss with GLP-1 receptor agonists ranges from fat-free mass (FFM) decreases of 25% to 39% of the total weight lost over 36 to 72 weeks

doi:10.1104/pp.118.4.1327

Across tested doses and routes, the elimination half-life remained under 30 minutes, with full plasma clearance occurring within 24 hours

-glucan is also effective against inflammatory bowel diseases (IBD), and constipation by ehanching the consistency of the stool and also proliferates goblet cells resulting in a thickened lubricating mucin layer which helps in improving the intestinal transit rate [63, 86]