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Both maternal chronic hypertension before pregnancy and gestational hypertension are associated with an ~40% increase in the odds of ASD in offspring (23, 230)

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M., Dietrich B., Hiersemenzel R.: harmacoelectroencephalographic and clinical effects of the cholinergic substance acetyl-L-carnitine in patients with organic brain syndrome

Another latching interaction occurs between the N-terminal and C-terminal portions of the ICH, where R282 (N-terminal) form a salt bridge with D519 of the (C-terminal, Fig