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The ensuing phagocytosis of RBCs may lead to iron overload within macrophages, which has been shown to cause progressive macrophage dysfunction, inflammatory M1 polarization, increased ferroptosis and exacerbated atherosclerosis 66,67,68,69,70,71

In this direction, the development of fluorescent dyes and protein-based ROS sensors subjected to different cellular locations provides essential insights into in vivo monitoring of ROS and redox dynamics of the cells with high precision and spatiotemporal resolution in the photosynthesizing organisms

Oncoscience 2 (5), 517532

D.TuliA.GnlenG.et al (2013)

SCFA deficits might also play a role: fecal levels of butyrate and other SCFAs are reported to be reduced in AD patients, which could exacerbate neuroinflammation by depriving microglia of anti-inflammatory signals [130]