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The concentration of neurometabolites was estimated relative to an unsuppressed water signal obtained from the same VOI [51]

Concomitantly, GLP-1RAs suppress the expression of lipogenic transcription factors and enzymes, including sterol regulatory element-binding protein 1c (SREBP-1c) and fatty acid synthase (FAS), resulting in reduced de novo lipogenesis

Overweight individuals with T2DM should reduce energy intake while maintaining a balanced diet rich in nutrient-dense foods like fruits, vegetables, whole grains, lean proteins, and healthy fats, limiting added sugars, sodium, and saturated fats [148]

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