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The phase 2 study to evaluate the efficacy, safety and tolerability of maridebart cafraglutide is currently ongoing (ClinicalTrials.gov number, NCT05669599)

Alpha-diversity was estimated using ACE, Chao1, Simpson, and Shannon indices

The Bottom Line GLP-1 drugs can benefit older adults with obesity, type 2 diabetes, or elevated cardiovascular risk

Ozempic, which is approved for people with diabetes but is prescribed off-label for weight loss, and Wegovy, which is approved for weight loss, can carry price tags of more than $1,000 a month

"I had tried all the medications that existed, supplements on top of supplements, and nothing really was able to fully grasp the insulin resistance piece for me," said a 20-something with PCOS