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Corroborating this hypothesis, HIF-1, a transcriptional factor known to target glycolytic genes, accumulates under GLP-1R stimulation

Funding This study was done with internal departmental funding from the Department of Anesthesia and Pain Management, Toronto Western Hospital, University Health Network (Toronto, ON, Canada)

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What GLP-1 Medications Actually Do GLP-1 (glucagon-like peptide-1) receptor agonists work by: Slowing gastric emptying Reducing appetite and food intake Improving glucose control Enhancing insulin response These effects are extremely effective for reducing caloric intake , which explains the dramatic short-term weight loss many patients see