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This shifts clinical emphasis toward interventions with stronger evidence for preserving lean masssuch as adequate dietary protein and resistance trainingwhile complementary biological modulators like postbiotics may improve insulin sensitivity and inflammatory tone, thereby supporting metabolic resilience rather than directly increasing thermogenesis

GLP-1 Agonists How They Work At their core, GLP-1 agonists mimic the actions of the GLP-1 hormone, which plays a pivotal role in regulating insulin release, slowing stomach emptying, and fostering feelings of satiety after meals

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Similar to the first study, RETA intervention led to a transient reduction in food intake and a 40% reduction in body weight that stabilized after two weeks for the duration of the study (Fig

The schematic drawing in Fig