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When mitochondria fail, the body cannot generate enough energy to meet even basic metabolic demands, directly causing the severe physical exhaustion and post-exertional malaise (PEM) that leaves patients bedbound after minor exertion

Systematically working through the following can help: Are you sleeping?Are you getting seven to nine hours most nights

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At the moment, there is no cure or disease-modifying treatment for painful diabetes-related peripheral neuropathy, but people can try medications and other interventions to manage the pain caused by nerve damage