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DISCUSSION In this NMA, GLP-1RA had a significantly better effect in reducing liver fat content and improving cardiometabolic risk parameters, including BMI and WC, in overweight or obese patients with NAFLD or NASH

This principle of timing-dependent effects applies to many peptide dosing strategies and underscores the importance of understanding proper peptide dosing protocols

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This cross-cellular signaling establishes a ferroptosismicroglianeuron amplification cascade (Duce et al., 2010)

Mean elimination half-life is about 2.7 hours