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The short answer is that it depends

It is freely soluble in water at a normal pH, a property that simplifies its formulation and administration

Foods that are harder to break downincluding whole corn kernels or corn-based starchescan exacerbate this response

Gastrointestinal Effects The most commonly reported adverse effects are gastrointestinal in nature, including: Nausea and vomiting (affecting 20-40% of patients initially, varying by agent and dose) [8] Diarrhoea or constipation Abdominal discomfort and bloating Reduced appetite In elderly patients, persistent nausea and vomiting can lead to dehydration and electrolyte imbalances more rapidly than in younger adults

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