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however, commercially viable product titres have not yet been reached, partly due to issues arising from the late steps of the biosynthetic pathway 6,7

The resulting holoenzyme dimer comprising the two subunits is catalytically more efficient and less subject to inhibition by glutathione (GSH) than GCLC alone

NeuroSci 3(1):130

Genetic variants of the p53 and p73 genes jointly increase risk of second primary malignancies in patients after index squamous cell carcinoma of the head and neck