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In people with metabolic dysfunction or obesity, this hormone signaling is often blunted or dysregulated, which is one of the biological reasons willpower alone is an incomplete tool for long-term weight management

The Institute for Functional Medicine (IFM) highlights glutathiones role in oxidative stress and chronic disease

In addition to regulating GPX4 function, ferroptosis agonists also degrade GPX4 via autophagy or the ubiquitinproteasome system [61,62,63]

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If you're working on something similar or have feedback on the architecture, I'd love to hear it in the comments.