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Quick-Reference DDI Summary Table | Co-administered Drug | GLP-1 RA Effect | Clinical Action | |---|---|---| | Insulin (basal) | Additive hypoglycemia | Reduce insulin 20% to 40% at initiation | | Sulfonylurea | Additive hypoglycemia | Halve the dose at initiation | | Warfarin | Possible INR increase | Check INR at 2 to 4 weeks

EClinicalMedicine 3(72):102624 [DOI] [PMC free article] [PubMed] [Google Scholar] 74.Jensen SBK, Srensen V, Sandsdal RM, Lehmann EW, Lundgren JR, Juhl CR et al (2024) Bone Health After Exercise Alone, GLP-1 Receptor Agonist Treatment, or Combination Treatment: A Secondary Analysis of a Randomized Clinical Trial