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prices (~$1,000/month), ICER found these near the $150k/QALY threshold for diabetic benefit, but well beyond for obesity alone

The ability of HO-1 to protect against SARS-CoV-2 infection is probably an emergency inducible defense mechanism to ameliorate OxS from heme-released oxidants 27

However, in the early stages of the disease, the role of LPO may be limited

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However, some authors recommend targeting 20-50 ug/mL