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Of the 223 enrolled participants, 95 (43%) were men, and 128 (57%) were women

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Symptoms are often most noticeable during treatment initiation or dose escalation

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Human cancer-associated fibroblasts enhance glutathione levels and antagonize drug-induced prostate cancer cell death

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However, the complexity of the UPR pathway remains the major challenge of dedicated therapies, limiting the number of dedicated compounds that make it to clinical use (as reviewed in Marciniak et al

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