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Studies confirm that in the mouse heat stroke model, inhibiting p53 function via siRNA or p53 inhibitor (PFT-) can significantly reduce abnormal hepatocyte apoptosis in heat stress-induced ALI [51]

The transsulfuration pathway involves the transfer of sulfur, converting homocysteine to cysteine, a precursor for glutathione production.* Glutathione then helps neutralize and eliminate: mercury [2], arsenic [3], cadmium [4], bisphenol A (BPA) [5], pesticide residues, and other toxins [6].* Poor MTHFR function can lead to elevated homocysteine, a byproduct of methionine metabolism

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10.1042/BST20230122 118 ZhouC.Segura-CovarrubiasG.TajimaN