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More frequent glucose monitoring during the switch helps detect any destabilization early

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Epigenetic Modifiers: Several clinical studies have confirmed that DNMTi combined with PD-1 inhibitors show good safety and preliminary efficacy in some patients with advanced solid tumors [176,177,178,179,180]

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In the first study, the SOD2 Ala 16 Val (C/T) (rs 4880) polymorphism, (Harris, 2017) was found to associate with the TT genotype, a genetic variation considered disadvantageous for the individual because of the reduced efficacy of the antioxidant enzyme