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TiO 2 NP-treated rats were fed with an MO leaf extract, and the expression of kidney 222 injury molecule 1 (KIM-1), NF-B, TNF-, and heat shock protein 70 (HSP-70) were markedly 223 decreased, while the expression of NRF-2 and heme oxygenase 1 (HO-1) were significantly 224 upregulated compared with those in control groups

described the activation of mammalian target of rapamycin (mTOR) as a crucial pathway for neuron protection, and that GLP-1RA affects mTOR activity by reducing caspase-3 and caspase-8 (51)

glutathione (GSH) is one of our most powerful allies in the fight against free radicals and the oxidative stress they cause

Drug approval databases for Wegovy, Zepbound, Mounjaro, Saxenda