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In addition, both TTP and gAgAP downregulated transcription levels of angiotensin II receptor type 1 ( agtr1 ) and miR-132/-212, with TTP producing a comparable reduction in agtr1 to captopril and a significant decrease in miR-132/-212 expression

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Cohen himself tried to develop it as a drug, but the peptide was so unstable that it broke down within minutes

A 2023 crossover trial in fatigued office workers found 500 mcg daily for 8 weeks slashed fatigue scores by 25%, linked to optimized homocysteine metabolism