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GDF8 and activin A are the key negative regulators of muscle mass in postmenopausal females: a randomized phase I trial

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The patients represent different lives and starting points, but the same underlying story dispelling the myth that [GLP-1 use] is just for vanity, Rahmanian said

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Many patients with metabolic syndrome have normal LDL but severely elevated triglycerides

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For example, SBP reductions were only 1.2 mmHg in the LEADER study and 1.7 mmHg in the REWIND study (54, 67), yet, the GLP-1RAmediated reduction in ASCVD reduction was comparable to that observed in the other CVOTs (48)

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